PCMM Signature
Image: Lymph node sample from Carroll Lab, imaged by Harry Leung of PCMM Microscopy Core.

A 250 micron projection into a mouse popliteal lymph node where immune cells (red and yellow) congregate; imaged with multiphoton microscopy. Collagen fibers (white and purple) forming the lymph node capsule were visualized with second harmonic generation.

The Program in Cellular and Molecular Medicine at Boston Children’s Hospital is an interdisciplinary research program affiliated with Harvard Medical School.  PCMM’s faculty brings together some of the world’s most distinguished investigators in the fields of immunology, genetics, structural biology, cell biology, cancer biology, microbiology, and neuroscience to address basic scientific questions with the ultimate goal of treatment and cure of disease. The program’s 15 laboratories and associated facilities reside within the vibrant biomedical research community of the Longwood Medical Area in Boston.

Composite-ctx939

UPCOMING SEMINAR

October 22, 2026
Lenardo_Michael_Portrait
Michael Lenardo, MD

Chief Scientific Officer
Calico Labs

October Seminar

Michael J. Lenardo is a molecular immunologist and geneticist recognized for his work on fundamental immunological mechanisms. He is particularly known for discovering the genetic basis, pathogenesis, and treatment of several congenital disorders of the immune system.
RESEARCH HIGHLIGHTS

Linear RAG scanning mediates editing of Igκ variable region repertoires

The laboratory of Dr. Frederick Alt, PhD has recently solved the long-standing puzzle of how the immune system edits autoreactive antibodies. Summarized by Clear Sky Science.

PCMM NEWS

Julia Li joins PCMM

Julia Li, PhD has joined the Boston Children’s faculty as an Investigator of the Program in Cellular and Molecular Medicine (PCMM) and the Harvard Medical School faculty as an Assistant Professor of Genetics. She joins us from University of California at San Diego, where she was a postdoctoral fellow in the laboratory of Don Cleveland and received the Damon Runyon-Dale F. Frey Award for Breakthrough Scientists.

LEARN MORE >

September 28-30, 2026
Sea Crest Beach Hotel

SAVE THE DATE

PCMM Scientific Retreat 2026

LEARN MORE >